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Antimicrobial resistance is a crisis that must be managed with the utmost urgency. The post-antibiotic era is not a distant threat, but a very real possibility for the 21st century.

Margaret Chan

WHO statement on antimicrobial resistance, 2012 · Gecheckt op 3 maart 2026
Antimicrobial resistance is a crisis that must be managed with the utmost urgency. The post-antibiotic era is not a distant threat, but a very real possibility for the 21st century.

Analyse

Chan’s statement aligns with **WHO reports from 2012–2014**, which explicitly labeled AMR a global health emergency and warned of a return to pre-antibiotic conditions if no action was taken. The **2019 UN Interagency Coordination Group (IACG) report** and **CDC’s 2019 AMR Threats Report** reaffirmed these risks, citing rising resistance rates in critical pathogens like *E. coli* and *Klebsiella*. Her framing of the threat as immediate—not distant—was prescient, given subsequent data showing **~1.27 million deaths annually attributed to AMR** (2019 *Lancet* study). No credible evidence contradicts her core claim.

Achtergrond

Antimicrobial resistance (AMR) occurs when microbes evolve to resist drugs like antibiotics, rendering treatments ineffective. By 2012, **multi-drug-resistant tuberculosis (MDR-TB)** and **methicillin-resistant *Staphylococcus aureus* (MRSA)** were already major concerns, with WHO declaring AMR a top-3 global health threat. Chan’s tenure as WHO Director-General (2006–2017) coincided with escalating alarms from organizations like the **CDC, O’Neill Commission (2016), and G20**, all echoing her urgency.

Samenvatting verdict

Margaret Chan’s 2012 warning about antimicrobial resistance (AMR) as an urgent crisis and the looming 'post-antibiotic era' is accurate and widely supported by scientific and public health consensus.

Geraadpleegde bronnen

— World Health Organization. (2012). *Antimicrobial resistance: A global report on surveillance*. https://www.who.int/publications/i/item/9789241564748
— World Health Organization. (2014). *Antimicrobial resistance: Global report on surveillance*. https://www.who.int/publications/i/item/9789241564748
— UN Interagency Coordination Group on AMR. (2019). *No time to wait: Securing the future from drug-resistant infections*. https://www.who.int/publications/i/item/no-time-to-wait-securing-the-future-from-drug-resistant-infections
— Murray, C.J.L. et al. (2022). *Global burden of bacterial antimicrobial resistance in 2019*. *The Lancet*, 399(10325), 629–655. https://doi.org/10.1016/S0140-6736(21)02724-0
— Centers for Disease Control and Prevention. (2019). *Antibiotic Resistance Threats in the United States, 2019*. https://www.cdc.gov/drugresistance/pdf/threats-report/2019-ar-threats-report-508.pdf
— Review on Antimicrobial Resistance. (2016). *Tackling drug-resistant infections globally: Final report*. https://amr-review.org/sites/default/files/160525_Final%20paper_with%20cover.pdf