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We are like a species that has lost its history. We have this very patchy knowledge of our ancestors, and genetics is giving us a way to fill in the gaps.

Svante Pääbo

Interview with *The Guardian*, discussing Neanderthal genome research, 2014 · Checked on 3 March 2026
We are like a species that has lost its history. We have this very patchy knowledge of our ancestors, and genetics is giving us a way to fill in the gaps.

Analysis

Pääbo’s claim aligns with his pioneering contributions to Neanderthal genomics, including the 2010 publication of the first draft Neanderthal genome (*Science*), which revealed interbreeding between Neanderthals and modern humans (~1.5–2% Neanderthal DNA in non-African populations). His statement also mirrors the field’s broader shift toward using genetics to address gaps in the fossil record, such as the 2014 discovery of the Denisovans (another archaic human group) through DNA analysis alone. The metaphor of humans as a 'species that has lost its history' is a poetic but factually grounded characterization of pre-genomic paleoanthropology, where morphological evidence was sparse and often ambiguous. No credible contradictions to this framing exist in peer-reviewed literature.

Background

Before ancient DNA techniques (developed largely by Pääbo’s team at the Max Planck Institute), human evolutionary history relied on fragmentary fossils and archaeological artifacts, leaving significant uncertainties about relationships between species like *Homo sapiens*, Neanderthals, and Denisovans. Pääbo’s work—including the 2022 Nobel Prize in Physiology or Medicine—validated genetics as a tool to 'fill in the gaps,' e.g., by confirming Neanderthal-modern human hybridization and identifying previously unknown hominin groups. The *Guardian* interview occurred during a period of rapid discovery in the field, including the sequencing of high-quality Neanderthal and Denisovan genomes.

Verdict summary

Svante Pääbo’s 2014 statement accurately reflects the role of ancient DNA research in reconstructing human evolutionary history, as corroborated by his own work and broader scientific consensus.

Sources consulted

— Green, R. E., et al. (2010). *A Draft Sequence of the Neanderthal Genome.* Science, 328(5979), 710–722. [DOI:10.1126/science.1188021](https://doi.org/10.1126/science.1188021)
— Meyer, M., et al. (2012). *A High-Coverage Genome Sequence from an Archaic Denisovan Individual.* Science, 338(6104), 222–226. [DOI:10.1126/science.1224344](https://doi.org/10.1126/science.1224344)
— Prüfer, K., et al. (2014). *The Complete Genome Sequence of a Neanderthal from the Altai Mountains.* Nature, 505(7481), 43–49. [DOI:10.1038/nature12886](https://doi.org/10.1038/nature12886)
— The Nobel Prize in Physiology or Medicine 2022. (2022). *Press Release: Svante Pääbo.* [NobelPrize.org](https://www.nobelprize.org/prizes/medicine/2022/press-release/)
— Sample, I. (2014). *Neanderthal Genes Give Clues to Human Evolution and Disease.* The Guardian. [Link](https://www.theguardian.com/science/2014/jan/29/neanderthal-genome-human-evolution-disease) (Interview context)